What Are The Four Stages of Mesothelioma Cancer?
By
David
Arnold Livingston
One rare form of cancer is called Mesothelioma, a malignant tumor in
the mesothelial tissues of the lungs and the abdomen, arising from the
inhalation of asbestos. Its rarity is one of the reasons why a lot of
people are not aware of this kind of fatal disease. In fact, many people
die of Mesothelioma undiagnosed. Although there is now a growing
awareness of the hazards of asbestos to health, still many have not
heard of Mesothelioma and thus, have not understood its nature, cause,
signs and treatment. Even some physicians find it hard to detect
Mesothelioma because its symptoms are akin to other diseases like lung
cancer and pneumonia. Furthermore, it takes decades for a patient who
was exposed to asbestos to develop Mesothelioma — fifty years, at most.
Being unaware of Mesothelioma poses higher risks since it deters
diagnosis and treatment. A person undergoing treatment must know the
different stages of the cancer or the extent of the disease. Chances of
recovering from Mesothelioma and the kind of treatment depend on the
stage of the illness. There are basically two staging systems used for
Pleural Mesothelioma (lungs): TNM system and Brighan system. These
staging systems are also used in other kinds of cancers; however, the
first is commonly used. There is no established method in determining
the stage of the Peritoneal Mesothelioma cancer (abdominal) so the TNM
system is used.
There are three variables in the TNM system: tumor, lymph nodes and
metastasis. In the earliest stage of Mesothelioma, stage I, the
malignant Mesothelioma cells start to grow and multiply only one layer
of the pleura. The pleura is the membrane that encloses the lungs and
lines the wall of the chest cavity. However, there are some instances
wherein the pericardium (membrane that covers the heart) and diaphragm
cover are already affected. In this case, the cancer patient is still in
stage I Mesothelioma.
In the second stage, the two layers of the pleura are already
affected by Mesothelioma. Take note, however, that in this stage, only
one side of the body is affected. Normally, the pleura produces only
small amount of lubricating fluid that allows easy expanding and
contracting of the lungs. The excess fluid is absorbed by the blood and
the lymph vessels so there’s a balance between the amount of fluid
produced and removed. During the second stage Mesothelioma, fluid starts
to build up between the membrane of the lungs and the membrane of the
chest wall, resulting to pleural effusion. The increase in the volume of
fluid produced causes shortness of breath and chest pain. Other
Mesothelioma cancer patients experience dry and persistent cough.
Diagnosis of the pleural effusion is achieved through a chest x-ray.
Stage III Mesothelioma means that the malignant cells have already
spread to the chest wall, esophagus and the lymph nodes on one part of
the chest. The patient may suffer severe pain near the parts affected.
When not treated immediately or when the Mesothelioma patient doesn’t
respond well to medication, the cancer may advance to the fourth stage.
The fourth stage Mesothelioma is formidable since at this stage the
Mesothelioma cells have penetrated into the bloodstream and other organs
in the body like the liver, the bones and the brain. The lymph nodes on
the other side of the chest may also be affected by Mesothelioma in
stage IV.
Brighan staging system, on the other hand, determines whether the
Mesothelioma can be surgically removed or not and whether the lymph
nodes are affected or not. In stage I Mesothelioma, the lymph nodes are
not yet affected and the patient can still recover through surgery. In
stage II, surgery can still be executed but some lymph nodes have
already been infiltrated by the cancer cells. In stage III, the heart
and chest wall are already affected; thus, surgery is no longer
advisable. The lymph nodes in this stage, however, may or may not be
affected. In the final stage, stage IV Mesothelioma, cancer cells have
already gone to the bloodstream and other parts of the body like the
heart, brain, bone and liver. In most cases, a patient who has reached
stage IV Mesothelioma only has four to twenty-four months to live.
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